Mixing Methamphetamine and Pregabalin
- Methamphetamine also called
- meth, crystal, crystal meth, ice, tina, shard
- Pregabalin also called
- lyrica, pregablin, gabapentin, gaba
Unsafe
There is a significant risk of seizures from this combination. Amphetamines increase respiration rate allowing for a higher dose of sedatives than normal. If amphetamines wears off first, recreational dosages of pregabalin may overcome the individual and cause respiratory arrest. Both substances at recreational dosages cause strain of the heart and may lead to further dangerous heart complications.
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Can you mix Methamphetamine and Pregabalin?
Risk of serious physical or psychological harm. Not recommended under any circumstances.
This is a class-level answer, inherited from Amphetamines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.
- Methamphetamine
- Roughly twice as potent, and lasts three to four times as long
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
Rated unsafe. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.